How Isoproterenol Works in Mesotherapy

It can activate receptors on the surfaces of fat cells that detect several types of
chemical signals. One of these receptors is called the beta
adrenergic receptor (beta-AR). When the beta-ARs are triggered,
they tell fat cells to start breaking down the fats stored inside
them, which in turn causes the fat cells to shrink and even disappear.
Different
types of fat tissues have varying responses to isoproterenol based on the
amount of beta-ARs and alpha-2 ARs, which have the opposite effect of
beta-ARs when activated. Fat tissue in the abdomen has a higher ratio
of beta-ARs to alpha-2 ARs than fat tissue in the thighs and buttocks.
This makes abdominal fat more sensitive to mesotherapy than hip, thigh,
and buttocks fat.
ProsScientific
publications have described the breakdown of fat in tissue that has
been subjected to these injections. Two studies have shown that peoples'
thighs became smaller.
It does have an
FDA approved indication for treatment of other diseases.
ConsSome
common side effects when given for its normal use are: nervousness,
insomnia, restlessness, headaches, and others. As mentioned above, the hips, thighs, and buttocks are more difficult to treat.
The
general side effects of mesotherapy also apply.